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What Is Tamoxifen?

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Tamoxifen is an orally active medication that is found in the class of drugs called Selective Estrogen Receptor Modulators (SERMs). If you’re familiar with Clomid (Clomiphene Citrate) then it might be easier to understand what is Tamoxifen. That’s because they are both in the same class of drugs.

Tamoxifen Citrate is mostly sold under the brand name Nolvadex. But you could find this substance being sold as numerous other brands too. Tamoxifen is a drug that is FDA approved for preventing breast cancer in women. Is also approved for treating breast cancer both in men and women.

The compound might be prescribed for infertility in women, gynecomastia in men, early puberty as well as other uses too.

Tamoxifen is also a very popular compound among bodybuilders and all anabolic steroid users. Those people who use these compounds for their physique and performance enhancement purposes.


  • That’s because Tamoxifen Citrate (Nolvadex) can be used either during the use of steroids to prevent or treat gynecomastia. This side effect is capable of occurring as a result of running aromatized steroids.
  • Or it can be used for Post Cycle Therapy (PCT) protocols. Tamoxifen was proven very effective at increasing LH and total testosterone levels in the body. Is generally being helpful at recovering the body’s normal hormonal balance.

Tamoxifen Profile

As mentioned, Tamoxifen Citrate is a Selective Estrogen Receptor Modulator (SERM). Therefore, the compound is working by selectively binding to estrogen receptors blocking their actions. As mentioned, similarly to Clomiphene Citrate.

This compound is not lowering total estrogen levels in the body like Aromatase Inhibitors (AIs) do.

That’s why Nolvadex is helpful for gynecomastia treatment, but is not very helpful for other estrogen related side effects. They may occur from running anabolic steroids.

This is the reason why Nolvadex (Tamoxifen) is rarely used during the cycle of steroids. Nolva is mostly seen as an effective PCT drug.

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Tamoxifen in Bodybuilding

As earlier mentioned, men who are prone to get gynecomastia issues may add Tamoxifen Citrate to their anabolic steroid cycle to stay away from gyno. The compound is added when sensitive-to-gynecomastia men run aromatized steroids like Testosterone or Dianabol and are likely to get gyno.

  • But remember that Tamoxifen won’t help you against other estrogen related side effects like water retention, high blood pressure, erectile dysfunction, bloating, and others.

That’s why AIs are mostly used during the cycle whilst SERMs are mostly used for PCT plans. Tamoxifen is greatly helping to increase LH and total testosterone. That’s greatly helping the person to recover back from a cycle, that’s why it is a popular product for PCT plans.

In fact, Tamoxifen with Clomiphene combined is considered by far one of the most popular and effective recovery options for PCT regimens.

Tamoxifen helps by stimulating hypophysis. This results in more gonadotropins, therefore in more LH and FSH and finally – more testosterone. It helps the body maintain high testosterone levels and helps recover much faster.


Tamoxifen vs Clomiphene

Both these compounds are SERMs and they are similar in terms of how they work (binding to estrogen receptors), side effects, and final results.

  • Nonetheless, they are still different – milligram per milligram Nolvadex is considered stronger than Clomid, especially when talking about estrogen receptors in breast tissues.
  • But on the other hand, Clomid is better for infertility treatment for women.

When talking about bodybuilding purposes and PCT plans, there is not a better one for everyone.

Some might find Tamoxifen better, others Clomiphene better.

Is up to the user to decide what is best for their needs through experience. Some get more benefits from Tamoxifen compared to Clomiphene, others get more side effects.

In the end, these 2 compounds work like salt and pepper together. They are working very well in synergy and that’s why most users go for a PCT plan with a combination with Nolvadex and Clomid.

Tamoxifen Dosage

If you run Tamoxifen for PCT plans, generally, the dosage is 40 mg a day for the first 2 weeks of PCT and 20 mg a day for the last 2 weeks of a total of 4 weeks PCT plan.

  • Nonetheless, dosages can be adjusted according to your needs.

PCT plan length may be adjusted according to your needs too and as mentioned – most PCT plans contain both these compounds combined together.

In terms of side effects – Nolvadex (Tamoxifen) is rarely offering any side effects because most men tolerate it very well. Side effects are mostly a sign of too high doses of the compound used meaning that they should be reduced.

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