Cabergoline is an orally active medication that is considered a very powerful dopamine receptor agonist. There are a lot of studies done on this compound (which is a fungi derivative) that prove that Cabergoline does an amazing job in inhibiting prolactin.
There are other compounds that are working in very similar ways as Cabergoline (sold as brand Dostinex, Caber, Cabaser, and many others). However, Cabergoline is remaining the favorite compound both in medicine as well as for bodybuilding purposes. Another drug working similarly is called Bromocriptine, which is an older compound than Caber. However, Bromocriptine has a shorter half life and is likely to offer more side effects, hence Cabergoline remains favored.
Cabergoline has been discovered many years ago by a company, which is currently owned by Pfizer. Later it was approved by FDA for the purpose of treating health issues associated with high prolactin levels.
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Cabergoline In Medicine
As much as it looks, Cabergoline (Dostinex) is having a lot of different uses in the medical world. By far one of the most popular uses of Cabergoline is to treat tumors and cancers that are being caused by high prolactin levels. This is the most popular drug when it comes to lowering prolactin levels.
Therefore, it can be used for:
- Hyperprolactinemia
- Treatment of uterine fibroids
- Various dysfunctions associated with hyperprolactinemia
- Parkinson’s disease
- Cushing’s disease
- As well as other issues, even off label for the purpose of reduced libido as an adjunct to SSRI antidepressants.
How Cabergoline Works?
Cabergoline is considered a very long acting dopamine D2 receptor agonist lowering prolactin levels in the pituitary. Prolactin is a powerful hormone that is best known for producing milk in females. Nonetheless, this hormone is having many other functions both in males and females.
By using Cabergoline (Dostinex) the pituitary gland does not secrete prolactin hormone and therefore, levels drop down. In males, the effects of prolactin are most noticeable after ejaculation – making the male lose interest in sex.
Cabergoline in Bodybuilding
Cabergoline uses in bodybuilding are different, although there’s one most popular use.
For example, it is mainly used by bodybuilders when they are running steroids that are known to increase levels of prolactin and good examples of that are Trenbolone and Nandrolone.
In case these compounds are used for way too long and/ or in way too high doses, you are very likely to suffer from high prolactin levels, which may lead to low sex drive, prolactin based gynecomastia, and other issues.
But it has some other uses in bodybuilding that are not as popular, still, some use it for such purposes:
Like an adrenaline rush because it is a dopamine agonist so it offers improved motor skills during a competition being able to ignore more pains. Because of the same dopamine agonist effect – you are getting less cravings for junk food. Fewer cravings = more weight loss. And lastly, due to the exact same effect, Cabergoline may also help with sleep as well.
In the end, most people have Cabergoline handy, especially when running Trenbolone based compounds. They are likely to suffer from low sex drive (as explained, when a man ejaculates, prolactin levels spike up making him lose interest in sex, and Trenbolone or Nandrolone may increase prolactin levels working in the same way).
Cabergoline lowers them down.
Cabergoline Side Effects
As much as you can guess, lowering down a hormone might not be the best idea as long as you’re not doing it properly.
- Usually, side effects include somnolence or insomnia, constipation or diarrhea, you may suffer from nausea or stomach issues, sometimes hypotension.
But bodybuilders who are running steroids are very unlikely to suffer from hypotension from Caber. Plus to that, by taking it with a large meal – you are very unlikely to suffer from any intestinal issues either.
Side effects of Cabergoline are mostly seen in patients suffering from health conditions. Is because they run this compound for longer periods in higher doses than bodybuilders.
If a steroid user adds Cabergoline to his cycle and uses it properly – side effects are unlikely to occur.
Cabergoline Dosage and Administration
As it was mentioned, Cabergoline has a long half life, which is about 3 days. Much longer compared to Bromocriptine which is only 12 hours.
If Cabergoline is given for a medical purpose – use it exactly as recommended by the doctor.
But there’s no need to use Cabergoline on a daily basis for the purpose of bodybuilding.
This is a very powerful medication with very long half life. 
- Half a tablet of Cabergoline which usually is 0.25 mg (most of them come as 0.5 mg per tablet) is going to be enough to be administered once every 3 days. This means that you only need to run one tablet (0.5 mg) per week!
At least, this dosage is going to be enough for most steroid users. Of course, the dosage can be adjusted according to your needs. But we recommend staying away from abusive dosages.
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